Sexual dysfunction during treatment with serotonergic and noradrenergic antidepressants: Clinical description and the role of the 5-HTTLPR
Identifieur interne : 000897 ( Main/Exploration ); précédent : 000896; suivant : 000898Sexual dysfunction during treatment with serotonergic and noradrenergic antidepressants: Clinical description and the role of the 5-HTTLPR
Auteurs : Jana Strohmaier [Allemagne] ; Stefan Wüst [Allemagne] ; Rudolf Uher [Royaume-Uni] ; Neven Henigsberg [Croatie] ; Ole Mors [Danemark] ; Joanna Hauser [Pologne] ; Daniel Souery [Belgique] ; Astrid Zobel [Allemagne] ; Mojca Z. Dernovsek [Slovénie] ; Fabian Streit [Allemagne] ; Christine Schm L [Allemagne] ; Dejan Kozel [Slovénie] ; Anna Placentino [Italie] ; Anne Farmer [Royaume-Uni] ; Peter Mcguffin [Royaume-Uni] ; Katherine J. Aitchison [Royaume-Uni] ; Marcella Rietschel [Allemagne]Source :
- The World Journal of Biological Psychiatry [ 1562-2975 ] ; 2011.
Abstract
Sexual dysfunction (SD) is a frequently reported side-effect of antidepressant treatment, particularly of selective serotonin reuptake inhibitors (SSRIs). In the multicentre clinical and pharmacogenetic GENDEP study (Genome-based Therapeutic Drugs for Depression), the effect of the serotonin transporter gene promoter polymorphism
A total of 494 subjects with an episode of DSM-IV major depression were randomly assigned to treatment with escitalopram or nortriptyline. Over 12 weeks, depressive symptoms and SD were measured weekly with the Montgomery-Asberg Depression Rating Scale, the Antidepressant Side-Effect Checklist, the UKU Side Effect Rating Scale, and the Sexual Functioning Questionnaire.
The incidence of reported SD after 12 weeks of treatment was relatively low, and did not differ significantly between antidepressants (14.9% escitalopram, 19.7% nortriptyline). There was no significant interaction between the
In GENDEP, rates of reported SD during treatment were lower than those described in previous reports. There was no apparent effect of the
Url:
DOI: 10.3109/15622975.2011.559270
PubMed: 21388237
PubMed Central: 3279131
Affiliations:
- Allemagne, Belgique, Croatie, Danemark, Italie, Pologne, Royaume-Uni, Slovénie
- Bade-Wurtemberg, District de Karlsruhe, Rhénanie-Palatinat
- Mannheim, Trèves (Allemagne)
- Université de Trèves
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 000183
- to stream Pmc, to step Curation: 000183
- to stream Pmc, to step Checkpoint: 000124
- to stream Ncbi, to step Merge: 000457
- to stream Ncbi, to step Curation: 000457
- to stream Ncbi, to step Checkpoint: 000457
- to stream Main, to step Merge: 000923
- to stream Main, to step Curation: 000897
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Sexual dysfunction during treatment with serotonergic and noradrenergic antidepressants: Clinical description and the role of the <italic>5-HTTLPR</italic></title><author><name sortKey="Strohmaier, Jana" sort="Strohmaier, Jana" uniqKey="Strohmaier J" first="Jana" last="Strohmaier">Jana Strohmaier</name><affiliation wicri:level="3"><nlm:aff id="au1">Central Institute of Mental Health, Division of Genetic Epidemiology in Psychiatry, Mannheim, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Central Institute of Mental Health, Division of Genetic Epidemiology in Psychiatry, Mannheim</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Mannheim</settlement></placeName></affiliation></author><author><name sortKey="Wust, Stefan" sort="Wust, Stefan" uniqKey="Wust S" first="Stefan" last="Wüst">Stefan Wüst</name><affiliation wicri:level="3"><nlm:aff id="au1">Central Institute of Mental Health, Division of Genetic Epidemiology in Psychiatry, Mannheim, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Central Institute of Mental Health, Division of Genetic Epidemiology in Psychiatry, Mannheim</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Mannheim</settlement></placeName></affiliation></author><author><name sortKey="Uher, Rudolf" sort="Uher, Rudolf" uniqKey="Uher R" first="Rudolf" last="Uher">Rudolf Uher</name><affiliation wicri:level="1"><nlm:aff id="au2">Medical Research Council (MRC) Social, Genetic, and Developmental Psychiatry Research Centre, Institute of Psychiatry, King's College London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Medical Research Council (MRC) Social, Genetic, and Developmental Psychiatry Research Centre, Institute of Psychiatry, King's College London</wicri:regionArea><wicri:noRegion>King's College London</wicri:noRegion></affiliation></author><author><name sortKey="Henigsberg, Neven" sort="Henigsberg, Neven" uniqKey="Henigsberg N" first="Neven" last="Henigsberg">Neven Henigsberg</name><affiliation wicri:level="1"><nlm:aff id="au3">Croatian Institute for Brain Research, Medical School, University of Zagreb, Croatia</nlm:aff><country xml:lang="fr">Croatie</country><wicri:regionArea>Croatian Institute for Brain Research, Medical School, University of Zagreb</wicri:regionArea><wicri:noRegion>University of Zagreb</wicri:noRegion></affiliation></author><author><name sortKey="Mors, Ole" sort="Mors, Ole" uniqKey="Mors O" first="Ole" last="Mors">Ole Mors</name><affiliation wicri:level="1"><nlm:aff id="au4">Aarhus University Hospital, Risskov, Denmark</nlm:aff><country xml:lang="fr">Danemark</country><wicri:regionArea>Aarhus University Hospital, Risskov</wicri:regionArea><wicri:noRegion>Risskov</wicri:noRegion></affiliation></author><author><name sortKey="Hauser, Joanna" sort="Hauser, Joanna" uniqKey="Hauser J" first="Joanna" last="Hauser">Joanna Hauser</name><affiliation wicri:level="1"><nlm:aff id="au5">Laboratory of Psychiatric Genetics, Department of Psychiatry, Poznan University of Medical Sciences, Poland</nlm:aff><country xml:lang="fr">Pologne</country><wicri:regionArea>Laboratory of Psychiatric Genetics, Department of Psychiatry, Poznan University of Medical Sciences</wicri:regionArea><wicri:noRegion>Poznan University of Medical Sciences</wicri:noRegion></affiliation></author><author><name sortKey="Souery, Daniel" sort="Souery, Daniel" uniqKey="Souery D" first="Daniel" last="Souery">Daniel Souery</name><affiliation wicri:level="1"><nlm:aff id="au6">Laboratoire de Psychologie Médicate, Université Libre de Bruxelles and Psy Pluriel – Centre Européen de Psychologie Médicale, Belgium</nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea>Laboratoire de Psychologie Médicate, Université Libre de Bruxelles and Psy Pluriel – Centre Européen de Psychologie Médicale</wicri:regionArea><wicri:noRegion>Université Libre de Bruxelles and Psy Pluriel – Centre Européen de Psychologie Médicale</wicri:noRegion></affiliation></author><author><name sortKey="Zobel, Astrid" sort="Zobel, Astrid" uniqKey="Zobel A" first="Astrid" last="Zobel">Astrid Zobel</name><affiliation wicri:level="1"><nlm:aff id="au7">Department of Psychiatry, University of Bonn, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Psychiatry, University of Bonn</wicri:regionArea><wicri:noRegion>University of Bonn</wicri:noRegion><wicri:noRegion>University of Bonn</wicri:noRegion><wicri:noRegion>University of Bonn</wicri:noRegion></affiliation></author><author><name sortKey="Dernovsek, Mojca Z" sort="Dernovsek, Mojca Z" uniqKey="Dernovsek M" first="Mojca Z" last="Dernovsek">Mojca Z. Dernovsek</name><affiliation wicri:level="1"><nlm:aff id="au8">Educational and Research Institute Ozara, Ljubljana, Slovenia</nlm:aff><country xml:lang="fr">Slovénie</country><wicri:regionArea>Educational and Research Institute Ozara, Ljubljana</wicri:regionArea><wicri:noRegion>Ljubljana</wicri:noRegion></affiliation></author><author><name sortKey="Streit, Fabian" sort="Streit, Fabian" uniqKey="Streit F" first="Fabian" last="Streit">Fabian Streit</name><affiliation wicri:level="3"><nlm:aff id="au1">Central Institute of Mental Health, Division of Genetic Epidemiology in Psychiatry, Mannheim, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Central Institute of Mental Health, Division of Genetic Epidemiology in Psychiatry, Mannheim</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Mannheim</settlement></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="au9">Institute of Psychobiology, University of Trier, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Psychobiology, University of Trier</wicri:regionArea><placeName><settlement type="city">Trèves (Allemagne)</settlement><region type="land" nuts="1">Rhénanie-Palatinat</region></placeName><orgName type="university">Université de Trèves</orgName></affiliation></author><author><name sortKey="Schm L, Christine" sort="Schm L, Christine" uniqKey="Schm L C" first="Christine" last="Schm L">Christine Schm L</name><affiliation wicri:level="3"><nlm:aff id="au1">Central Institute of Mental Health, Division of Genetic Epidemiology in Psychiatry, Mannheim, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Central Institute of Mental Health, Division of Genetic Epidemiology in Psychiatry, Mannheim</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Mannheim</settlement></placeName></affiliation></author><author><name sortKey="Kozel, Dejan" sort="Kozel, Dejan" uniqKey="Kozel D" first="Dejan" last="Kozel">Dejan Kozel</name><affiliation wicri:level="1"><nlm:aff id="au10">Institute of Public Health, Ljubljana, Slovenia</nlm:aff><country xml:lang="fr">Slovénie</country><wicri:regionArea>Institute of Public Health, Ljubljana</wicri:regionArea><wicri:noRegion>Ljubljana</wicri:noRegion></affiliation></author><author><name sortKey="Placentino, Anna" sort="Placentino, Anna" uniqKey="Placentino A" first="Anna" last="Placentino">Anna Placentino</name><affiliation wicri:level="1"><nlm:aff id="au11">Psychiatric Unit 23, Department of Mental Health, Spedali Civili Hospital and Biological Psychiatry Unit, Centro San Giovanni di Dio IRCCS-FBF, Brescia, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Psychiatric Unit 23, Department of Mental Health, Spedali Civili Hospital and Biological Psychiatry Unit, Centro San Giovanni di Dio IRCCS-FBF, Brescia</wicri:regionArea><wicri:noRegion>Brescia</wicri:noRegion></affiliation></author><author><name sortKey="Farmer, Anne" sort="Farmer, Anne" uniqKey="Farmer A" first="Anne" last="Farmer">Anne Farmer</name><affiliation wicri:level="1"><nlm:aff id="au2">Medical Research Council (MRC) Social, Genetic, and Developmental Psychiatry Research Centre, Institute of Psychiatry, King's College London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Medical Research Council (MRC) Social, Genetic, and Developmental Psychiatry Research Centre, Institute of Psychiatry, King's College London</wicri:regionArea><wicri:noRegion>King's College London</wicri:noRegion></affiliation></author><author><name sortKey="Mcguffin, Peter" sort="Mcguffin, Peter" uniqKey="Mcguffin P" first="Peter" last="Mcguffin">Peter Mcguffin</name><affiliation wicri:level="1"><nlm:aff id="au2">Medical Research Council (MRC) Social, Genetic, and Developmental Psychiatry Research Centre, Institute of Psychiatry, King's College London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Medical Research Council (MRC) Social, Genetic, and Developmental Psychiatry Research Centre, Institute of Psychiatry, King's College London</wicri:regionArea><wicri:noRegion>King's College London</wicri:noRegion></affiliation></author><author><name sortKey="Aitchison, Katherine J" sort="Aitchison, Katherine J" uniqKey="Aitchison K" first="Katherine J" last="Aitchison">Katherine J. Aitchison</name><affiliation wicri:level="1"><nlm:aff id="au2">Medical Research Council (MRC) Social, Genetic, and Developmental Psychiatry Research Centre, Institute of Psychiatry, King's College London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Medical Research Council (MRC) Social, Genetic, and Developmental Psychiatry Research Centre, Institute of Psychiatry, King's College London</wicri:regionArea><wicri:noRegion>King's College London</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="au12">Division of Psychological Medicine and Psychiatry, Institute of Psychiatry, King's College London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Psychological Medicine and Psychiatry, Institute of Psychiatry, King's College London</wicri:regionArea><wicri:noRegion>King's College London</wicri:noRegion></affiliation></author><author><name sortKey="Rietschel, Marcella" sort="Rietschel, Marcella" uniqKey="Rietschel M" first="Marcella" last="Rietschel">Marcella Rietschel</name><affiliation wicri:level="3"><nlm:aff id="au1">Central Institute of Mental Health, Division of Genetic Epidemiology in Psychiatry, Mannheim, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Central Institute of Mental Health, Division of Genetic Epidemiology in Psychiatry, Mannheim</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Mannheim</settlement></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">21388237</idno><idno type="pmc">3279131</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279131</idno><idno type="RBID">PMC:3279131</idno><idno type="doi">10.3109/15622975.2011.559270</idno><date when="2011">2011</date><idno type="wicri:Area/Pmc/Corpus">000183</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000183</idno><idno type="wicri:Area/Pmc/Curation">000183</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000183</idno><idno type="wicri:Area/Pmc/Checkpoint">000124</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000124</idno><idno type="wicri:Area/Ncbi/Merge">000457</idno><idno type="wicri:Area/Ncbi/Curation">000457</idno><idno type="wicri:Area/Ncbi/Checkpoint">000457</idno><idno type="wicri:doubleKey">1562-2975:2011:Strohmaier J:sexual:dysfunction:during</idno><idno type="wicri:Area/Main/Merge">000923</idno><idno type="wicri:Area/Main/Curation">000897</idno><idno type="wicri:Area/Main/Exploration">000897</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Sexual dysfunction during treatment with serotonergic and noradrenergic antidepressants: Clinical description and the role of the <italic>5-HTTLPR</italic></title><author><name sortKey="Strohmaier, Jana" sort="Strohmaier, Jana" uniqKey="Strohmaier J" first="Jana" last="Strohmaier">Jana Strohmaier</name><affiliation wicri:level="3"><nlm:aff id="au1">Central Institute of Mental Health, Division of Genetic Epidemiology in Psychiatry, Mannheim, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Central Institute of Mental Health, Division of Genetic Epidemiology in Psychiatry, Mannheim</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Mannheim</settlement></placeName></affiliation></author><author><name sortKey="Wust, Stefan" sort="Wust, Stefan" uniqKey="Wust S" first="Stefan" last="Wüst">Stefan Wüst</name><affiliation wicri:level="3"><nlm:aff id="au1">Central Institute of Mental Health, Division of Genetic Epidemiology in Psychiatry, Mannheim, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Central Institute of Mental Health, Division of Genetic Epidemiology in Psychiatry, Mannheim</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Mannheim</settlement></placeName></affiliation></author><author><name sortKey="Uher, Rudolf" sort="Uher, Rudolf" uniqKey="Uher R" first="Rudolf" last="Uher">Rudolf Uher</name><affiliation wicri:level="1"><nlm:aff id="au2">Medical Research Council (MRC) Social, Genetic, and Developmental Psychiatry Research Centre, Institute of Psychiatry, King's College London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Medical Research Council (MRC) Social, Genetic, and Developmental Psychiatry Research Centre, Institute of Psychiatry, King's College London</wicri:regionArea><wicri:noRegion>King's College London</wicri:noRegion></affiliation></author><author><name sortKey="Henigsberg, Neven" sort="Henigsberg, Neven" uniqKey="Henigsberg N" first="Neven" last="Henigsberg">Neven Henigsberg</name><affiliation wicri:level="1"><nlm:aff id="au3">Croatian Institute for Brain Research, Medical School, University of Zagreb, Croatia</nlm:aff><country xml:lang="fr">Croatie</country><wicri:regionArea>Croatian Institute for Brain Research, Medical School, University of Zagreb</wicri:regionArea><wicri:noRegion>University of Zagreb</wicri:noRegion></affiliation></author><author><name sortKey="Mors, Ole" sort="Mors, Ole" uniqKey="Mors O" first="Ole" last="Mors">Ole Mors</name><affiliation wicri:level="1"><nlm:aff id="au4">Aarhus University Hospital, Risskov, Denmark</nlm:aff><country xml:lang="fr">Danemark</country><wicri:regionArea>Aarhus University Hospital, Risskov</wicri:regionArea><wicri:noRegion>Risskov</wicri:noRegion></affiliation></author><author><name sortKey="Hauser, Joanna" sort="Hauser, Joanna" uniqKey="Hauser J" first="Joanna" last="Hauser">Joanna Hauser</name><affiliation wicri:level="1"><nlm:aff id="au5">Laboratory of Psychiatric Genetics, Department of Psychiatry, Poznan University of Medical Sciences, Poland</nlm:aff><country xml:lang="fr">Pologne</country><wicri:regionArea>Laboratory of Psychiatric Genetics, Department of Psychiatry, Poznan University of Medical Sciences</wicri:regionArea><wicri:noRegion>Poznan University of Medical Sciences</wicri:noRegion></affiliation></author><author><name sortKey="Souery, Daniel" sort="Souery, Daniel" uniqKey="Souery D" first="Daniel" last="Souery">Daniel Souery</name><affiliation wicri:level="1"><nlm:aff id="au6">Laboratoire de Psychologie Médicate, Université Libre de Bruxelles and Psy Pluriel – Centre Européen de Psychologie Médicale, Belgium</nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea>Laboratoire de Psychologie Médicate, Université Libre de Bruxelles and Psy Pluriel – Centre Européen de Psychologie Médicale</wicri:regionArea><wicri:noRegion>Université Libre de Bruxelles and Psy Pluriel – Centre Européen de Psychologie Médicale</wicri:noRegion></affiliation></author><author><name sortKey="Zobel, Astrid" sort="Zobel, Astrid" uniqKey="Zobel A" first="Astrid" last="Zobel">Astrid Zobel</name><affiliation wicri:level="1"><nlm:aff id="au7">Department of Psychiatry, University of Bonn, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Psychiatry, University of Bonn</wicri:regionArea><wicri:noRegion>University of Bonn</wicri:noRegion><wicri:noRegion>University of Bonn</wicri:noRegion><wicri:noRegion>University of Bonn</wicri:noRegion></affiliation></author><author><name sortKey="Dernovsek, Mojca Z" sort="Dernovsek, Mojca Z" uniqKey="Dernovsek M" first="Mojca Z" last="Dernovsek">Mojca Z. Dernovsek</name><affiliation wicri:level="1"><nlm:aff id="au8">Educational and Research Institute Ozara, Ljubljana, Slovenia</nlm:aff><country xml:lang="fr">Slovénie</country><wicri:regionArea>Educational and Research Institute Ozara, Ljubljana</wicri:regionArea><wicri:noRegion>Ljubljana</wicri:noRegion></affiliation></author><author><name sortKey="Streit, Fabian" sort="Streit, Fabian" uniqKey="Streit F" first="Fabian" last="Streit">Fabian Streit</name><affiliation wicri:level="3"><nlm:aff id="au1">Central Institute of Mental Health, Division of Genetic Epidemiology in Psychiatry, Mannheim, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Central Institute of Mental Health, Division of Genetic Epidemiology in Psychiatry, Mannheim</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Mannheim</settlement></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="au9">Institute of Psychobiology, University of Trier, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Psychobiology, University of Trier</wicri:regionArea><placeName><settlement type="city">Trèves (Allemagne)</settlement><region type="land" nuts="1">Rhénanie-Palatinat</region></placeName><orgName type="university">Université de Trèves</orgName></affiliation></author><author><name sortKey="Schm L, Christine" sort="Schm L, Christine" uniqKey="Schm L C" first="Christine" last="Schm L">Christine Schm L</name><affiliation wicri:level="3"><nlm:aff id="au1">Central Institute of Mental Health, Division of Genetic Epidemiology in Psychiatry, Mannheim, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Central Institute of Mental Health, Division of Genetic Epidemiology in Psychiatry, Mannheim</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Mannheim</settlement></placeName></affiliation></author><author><name sortKey="Kozel, Dejan" sort="Kozel, Dejan" uniqKey="Kozel D" first="Dejan" last="Kozel">Dejan Kozel</name><affiliation wicri:level="1"><nlm:aff id="au10">Institute of Public Health, Ljubljana, Slovenia</nlm:aff><country xml:lang="fr">Slovénie</country><wicri:regionArea>Institute of Public Health, Ljubljana</wicri:regionArea><wicri:noRegion>Ljubljana</wicri:noRegion></affiliation></author><author><name sortKey="Placentino, Anna" sort="Placentino, Anna" uniqKey="Placentino A" first="Anna" last="Placentino">Anna Placentino</name><affiliation wicri:level="1"><nlm:aff id="au11">Psychiatric Unit 23, Department of Mental Health, Spedali Civili Hospital and Biological Psychiatry Unit, Centro San Giovanni di Dio IRCCS-FBF, Brescia, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Psychiatric Unit 23, Department of Mental Health, Spedali Civili Hospital and Biological Psychiatry Unit, Centro San Giovanni di Dio IRCCS-FBF, Brescia</wicri:regionArea><wicri:noRegion>Brescia</wicri:noRegion></affiliation></author><author><name sortKey="Farmer, Anne" sort="Farmer, Anne" uniqKey="Farmer A" first="Anne" last="Farmer">Anne Farmer</name><affiliation wicri:level="1"><nlm:aff id="au2">Medical Research Council (MRC) Social, Genetic, and Developmental Psychiatry Research Centre, Institute of Psychiatry, King's College London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Medical Research Council (MRC) Social, Genetic, and Developmental Psychiatry Research Centre, Institute of Psychiatry, King's College London</wicri:regionArea><wicri:noRegion>King's College London</wicri:noRegion></affiliation></author><author><name sortKey="Mcguffin, Peter" sort="Mcguffin, Peter" uniqKey="Mcguffin P" first="Peter" last="Mcguffin">Peter Mcguffin</name><affiliation wicri:level="1"><nlm:aff id="au2">Medical Research Council (MRC) Social, Genetic, and Developmental Psychiatry Research Centre, Institute of Psychiatry, King's College London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Medical Research Council (MRC) Social, Genetic, and Developmental Psychiatry Research Centre, Institute of Psychiatry, King's College London</wicri:regionArea><wicri:noRegion>King's College London</wicri:noRegion></affiliation></author><author><name sortKey="Aitchison, Katherine J" sort="Aitchison, Katherine J" uniqKey="Aitchison K" first="Katherine J" last="Aitchison">Katherine J. Aitchison</name><affiliation wicri:level="1"><nlm:aff id="au2">Medical Research Council (MRC) Social, Genetic, and Developmental Psychiatry Research Centre, Institute of Psychiatry, King's College London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Medical Research Council (MRC) Social, Genetic, and Developmental Psychiatry Research Centre, Institute of Psychiatry, King's College London</wicri:regionArea><wicri:noRegion>King's College London</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="au12">Division of Psychological Medicine and Psychiatry, Institute of Psychiatry, King's College London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Psychological Medicine and Psychiatry, Institute of Psychiatry, King's College London</wicri:regionArea><wicri:noRegion>King's College London</wicri:noRegion></affiliation></author><author><name sortKey="Rietschel, Marcella" sort="Rietschel, Marcella" uniqKey="Rietschel M" first="Marcella" last="Rietschel">Marcella Rietschel</name><affiliation wicri:level="3"><nlm:aff id="au1">Central Institute of Mental Health, Division of Genetic Epidemiology in Psychiatry, Mannheim, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Central Institute of Mental Health, Division of Genetic Epidemiology in Psychiatry, Mannheim</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Mannheim</settlement></placeName></affiliation></author></analytic><series><title level="j">The World Journal of Biological Psychiatry</title><idno type="ISSN">1562-2975</idno><idno type="eISSN">1814-1412</idno><imprint><date when="2011">2011</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec><title>Objectives</title><p>Sexual dysfunction (SD) is a frequently reported side-effect of antidepressant treatment, particularly of selective serotonin reuptake inhibitors (SSRIs). In the multicentre clinical and pharmacogenetic GENDEP study (Genome-based Therapeutic Drugs for Depression), the effect of the serotonin transporter gene promoter polymorphism <italic>5-HTTLPR</italic> on sexual function was investigated during treatment with escitalopram (SSRI) and nortriptyline (tricyclic antidepressant).</p></sec><sec><title>Methods</title><p>A total of 494 subjects with an episode of DSM-IV major depression were randomly assigned to treatment with escitalopram or nortriptyline. Over 12 weeks, depressive symptoms and SD were measured weekly with the Montgomery-Asberg Depression Rating Scale, the Antidepressant Side-Effect Checklist, the UKU Side Effect Rating Scale, and the Sexual Functioning Questionnaire.</p></sec><sec><title>Results</title><p>The incidence of reported SD after 12 weeks of treatment was relatively low, and did not differ significantly between antidepressants (14.9% escitalopram, 19.7% nortriptyline). There was no significant interaction between the <italic>5-HTTLPR</italic> and antidepressant on SD. Improvement in depressive symptoms and younger age were both associated with lower SD. The effect of age on SD may have been moderated by the <italic>5-HTTLPR</italic>.</p></sec><sec><title>Conclusions</title><p>In GENDEP, rates of reported SD during treatment were lower than those described in previous reports. There was no apparent effect of the <italic>5-HTTLPR</italic> on the observed decline in SD.</p></sec></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Ashton, Ak" uniqKey="Ashton A">AK Ashton</name></author><author><name sortKey="Mahmood, A" uniqKey="Mahmood A">A Mahmood</name></author><author><name sortKey="Iqbal, F" uniqKey="Iqbal F">F Iqbal</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Baldessarini, Rj" uniqKey="Baldessarini R">RJ Baldessarini</name></author><author><name sortKey="Marsh, E" uniqKey="Marsh E">E Marsh</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Baldwin, Ds" uniqKey="Baldwin D">DS Baldwin</name></author><author><name sortKey="Cooper, Ja" uniqKey="Cooper J">JA Cooper</name></author><author><name sortKey="Huusom, Ak" uniqKey="Huusom A">AK Huusom</name></author><author><name sortKey="Hindmarch, I" uniqKey="Hindmarch I">I Hindmarch</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Baldwin, Ds" uniqKey="Baldwin D">DS Baldwin</name></author><author><name sortKey="Reines, Eh" uniqKey="Reines E">EH Reines</name></author><author><name sortKey="Guiton, C" uniqKey="Guiton C">C Guiton</name></author><author><name sortKey="Weiller, E" uniqKey="Weiller E">E Weiller</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bishop, Jr" uniqKey="Bishop J">JR Bishop</name></author><author><name sortKey="Ellingrod, Vl" uniqKey="Ellingrod V">VL Ellingrod</name></author><author><name sortKey="Akroush, M" uniqKey="Akroush M">M Akroush</name></author><author><name sortKey="Moline, J" uniqKey="Moline J">J Moline</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bitran, D" uniqKey="Bitran D">D Bitran</name></author><author><name sortKey="Hull, Em" uniqKey="Hull E">EM Hull</name></author><author><name sortKey="Holmes, Gm" uniqKey="Holmes G">GM Holmes</name></author><author><name sortKey="Lookingland, Kj" uniqKey="Lookingland K">KJ Lookingland</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Christensen, Bs" uniqKey="Christensen B">BS Christensen</name></author><author><name sortKey="Gronbaek, M" uniqKey="Gronbaek M">M Gronbaek</name></author><author><name sortKey="Osier, M" uniqKey="Osier M">M Osier</name></author><author><name sortKey="Pedersen, Bv" uniqKey="Pedersen B">BV Pedersen</name></author><author><name sortKey="Graugaard, C" uniqKey="Graugaard C">C Graugaard</name></author><author><name sortKey="Frisch, M" uniqKey="Frisch M">M Frisch</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Clayton, Ah" uniqKey="Clayton A">AH Clayton</name></author><author><name sortKey="Pradko, Jf" uniqKey="Pradko J">JF Pradko</name></author><author><name sortKey="Croft, Ha" uniqKey="Croft H">HA Croft</name></author><author><name sortKey="Montano, Cb" uniqKey="Montano C">CB Montano</name></author><author><name sortKey="Leadbetter, Ra" uniqKey="Leadbetter R">RA Leadbetter</name></author><author><name sortKey="Bolden Watson, C" uniqKey="Bolden Watson C">C Bolden-Watson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Clayton, Ah" uniqKey="Clayton A">AH Clayton</name></author><author><name sortKey="Keller, A" uniqKey="Keller A">A Keller</name></author><author><name sortKey="Mcgarvey, El" uniqKey="Mcgarvey E">EL McGarvey</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Clayton, Ah" uniqKey="Clayton A">AH Clayton</name></author><author><name sortKey="Croft, Ha" uniqKey="Croft H">HA Croft</name></author><author><name sortKey="Horrigan, Jp" uniqKey="Horrigan J">JP Horrigan</name></author><author><name sortKey="Wightman, Ds" uniqKey="Wightman D">DS Wightman</name></author><author><name sortKey="Krishen, A" uniqKey="Krishen A">A Krishen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Clayton, A" uniqKey="Clayton A">A Clayton</name></author><author><name sortKey="Kornstein, S" uniqKey="Kornstein S">S Kornstein</name></author><author><name sortKey="Prakash, A" uniqKey="Prakash A">A Prakash</name></author><author><name sortKey="Mallinckrodt, C" uniqKey="Mallinckrodt C">C Mallinckrodt</name></author><author><name sortKey="Wohlreich, M" uniqKey="Wohlreich M">M Wohlreich</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Corona, G" uniqKey="Corona G">G Corona</name></author><author><name sortKey="Ricca, V" uniqKey="Ricca V">V Ricca</name></author><author><name sortKey="Bandini, E" uniqKey="Bandini E">E Bandini</name></author><author><name sortKey="Mannucci, E" uniqKey="Mannucci E">E Mannucci</name></author><author><name sortKey="Lotti, F" uniqKey="Lotti F">F Lotti</name></author><author><name sortKey="Boddi, V" uniqKey="Boddi V">V Boddi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Corona, G" uniqKey="Corona G">G Corona</name></author><author><name sortKey="Lee, Dm" uniqKey="Lee D">DM Lee</name></author><author><name sortKey="Ford, G" uniqKey="Ford G">G Ford</name></author><author><name sortKey="O Connor, Db" uniqKey="O Connor D">DB O'Connor</name></author><author><name sortKey="Maggi, M" uniqKey="Maggi M">M Maggi</name></author><author><name sortKey="O Neill, Tw" uniqKey="O Neill T">TW O'Neill</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="De Bakker, Pi" uniqKey="De Bakker P">PI de Bakker</name></author><author><name sortKey="Yelensky, R" uniqKey="Yelensky R">R Yelensky</name></author><author><name sortKey="Pe Er, I" uniqKey="Pe Er I">I Pe'er</name></author><author><name sortKey="Gabriel, Sb" uniqKey="Gabriel S">SB Gabriel</name></author><author><name sortKey="Daly, Mj" uniqKey="Daly M">MJ Daly</name></author><author><name sortKey="Altshuler, D" uniqKey="Altshuler D">D Altshuler</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Degner, D" uniqKey="Degner D">D Degner</name></author><author><name sortKey="Grohmann, R" uniqKey="Grohmann R">R Grohmann</name></author><author><name sortKey="Kropp, S" uniqKey="Kropp S">S Kropp</name></author><author><name sortKey="Ruther, E" uniqKey="Ruther E">E Ruther</name></author><author><name sortKey="Bender, S" uniqKey="Bender S">S Bender</name></author><author><name sortKey="Engel, Rr" uniqKey="Engel R">RR Engel</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Derogatis, Lr" uniqKey="Derogatis L">LR Derogatis</name></author><author><name sortKey="Burnett, Al" uniqKey="Burnett A">AL Burnett</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Done, Cj" uniqKey="Done C">CJ Done</name></author><author><name sortKey="Sharp, T" uniqKey="Sharp T">T Sharp</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Drago, A" uniqKey="Drago A">A Drago</name></author><author><name sortKey="De Ronchi, D" uniqKey="De Ronchi D">D De Ronchi</name></author><author><name sortKey="Serretti, A" uniqKey="Serretti A">A Serretti</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Freeman, B" uniqKey="Freeman B">B Freeman</name></author><author><name sortKey="Smith, N" uniqKey="Smith N">N Smith</name></author><author><name sortKey="Curtis, C" uniqKey="Curtis C">C Curtis</name></author><author><name sortKey="Huckett, L" uniqKey="Huckett L">L Huckett</name></author><author><name sortKey="Mill, J" uniqKey="Mill J">J Mill</name></author><author><name sortKey="Craig, Iw" uniqKey="Craig I">IW Craig</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Grohmann, R" uniqKey="Grohmann R">R Grohmann</name></author><author><name sortKey="Ruther, E" uniqKey="Ruther E">E Ruther</name></author><author><name sortKey="Engel, Rr" uniqKey="Engel R">RR Engel</name></author><author><name sortKey="Hippius, H" uniqKey="Hippius H">H Hippius</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Haberfellner, Em" uniqKey="Haberfellner E">EM Haberfellner</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hirschfeld, Rm" uniqKey="Hirschfeld R">RM Hirschfeld</name></author><author><name sortKey="Vornik, La" uniqKey="Vornik L">LA Vornik</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hsu, Jh" uniqKey="Hsu J">JH Hsu</name></author><author><name sortKey="Shen, Ww" uniqKey="Shen W">WW Shen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Huezo Diaz, P" uniqKey="Huezo Diaz P">P Huezo-Diaz</name></author><author><name sortKey="Uher, R" uniqKey="Uher R">R Uher</name></author><author><name sortKey="Smith, R" uniqKey="Smith R">R Smith</name></author><author><name sortKey="Rietschel, M" uniqKey="Rietschel M">M Rietschel</name></author><author><name sortKey="Henigsberg, N" uniqKey="Henigsberg N">N Henigsberg</name></author><author><name sortKey="Marusic, A" uniqKey="Marusic A">A Marusic</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hull, Em" uniqKey="Hull E">EM Hull</name></author><author><name sortKey="Lorrain, Ds" uniqKey="Lorrain D">DS Lorrain</name></author><author><name sortKey="Du, J" uniqKey="Du J">J Du</name></author><author><name sortKey="Matuszewich, L" uniqKey="Matuszewich L">L Matuszewich</name></author><author><name sortKey="Lumley, La" uniqKey="Lumley L">LA Lumley</name></author><author><name sortKey="Putnam, Sk" uniqKey="Putnam S">SK Putnam</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ising, M" uniqKey="Ising M">M Ising</name></author><author><name sortKey="Lucae, S" uniqKey="Lucae S">S Lucae</name></author><author><name sortKey="Binder, Eb" uniqKey="Binder E">EB Binder</name></author><author><name sortKey="Bettecken, T" uniqKey="Bettecken T">T Bettecken</name></author><author><name sortKey="Uhr, M" uniqKey="Uhr M">M Uhr</name></author><author><name sortKey="Ripke, S" uniqKey="Ripke S">S Ripke</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Janssen, Pk" uniqKey="Janssen P">PK Janssen</name></author><author><name sortKey="Bakker, Sc" uniqKey="Bakker S">SC Bakker</name></author><author><name sortKey="Rethelyi, J" uniqKey="Rethelyi J">J Rethelyi</name></author><author><name sortKey="Zwinderman, Ah" uniqKey="Zwinderman A">AH Zwinderman</name></author><author><name sortKey="Touw, Dj" uniqKey="Touw D">DJ Touw</name></author><author><name sortKey="Olivier, B" uniqKey="Olivier B">B Olivier</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kato, M" uniqKey="Kato M">M Kato</name></author><author><name sortKey="Serretti, A" uniqKey="Serretti A">A Serretti</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lanza Di Scalea, T" uniqKey="Lanza Di Scalea T">T Lanza di Scalea</name></author><author><name sortKey="Hanusa, Bh" uniqKey="Hanusa B">BH Hanusa</name></author><author><name sortKey="Wisner, Kl" uniqKey="Wisner K">KL Wisner</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Laumann, Eo" uniqKey="Laumann E">EO Laumann</name></author><author><name sortKey="Paik, A" uniqKey="Paik A">A Paik</name></author><author><name sortKey="Rosen, Rc" uniqKey="Rosen R">RC Rosen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Laumann, Eo" uniqKey="Laumann E">EO Laumann</name></author><author><name sortKey="Glasser, Db" uniqKey="Glasser D">DB Glasser</name></author><author><name sortKey="Neves, Rc" uniqKey="Neves R">RC Neves</name></author><author><name sortKey="Moreira, Ed" uniqKey="Moreira E">ED Moreira</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lee, Aw" uniqKey="Lee A">AW Lee</name></author><author><name sortKey="Pfaff, Dw" uniqKey="Pfaff D">DW Pfaff</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lin, E" uniqKey="Lin E">E Lin</name></author><author><name sortKey="Chen, Ps" uniqKey="Chen P">PS Chen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lingjaerde, O" uniqKey="Lingjaerde O">O Lingjaerde</name></author><author><name sortKey="Ahlfors, Ug" uniqKey="Ahlfors U">UG Ahlfors</name></author><author><name sortKey="Bech, P" uniqKey="Bech P">P Bech</name></author><author><name sortKey="Dencker, Sj" uniqKey="Dencker S">SJ Dencker</name></author><author><name sortKey="Elgen, K" uniqKey="Elgen K">K Elgen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Meltzer, Hy" uniqKey="Meltzer H">HY Meltzer</name></author><author><name sortKey="Young, M" uniqKey="Young M">M Young</name></author><author><name sortKey="Metz, J" uniqKey="Metz J">J Metz</name></author><author><name sortKey="Fang, Vs" uniqKey="Fang V">VS Fang</name></author><author><name sortKey="Schyve, Pm" uniqKey="Schyve P">PM Schyve</name></author><author><name sortKey="Arora, Rc" uniqKey="Arora R">RC Arora</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Montejo, At" uniqKey="Montejo A">AT Montejo</name></author><author><name sortKey="Llorca, G" uniqKey="Llorca G">G Llorca</name></author><author><name sortKey="Izquierdo, Ja" uniqKey="Izquierdo J">JA Izquierdo</name></author><author><name sortKey="Rico Villademoros, F" uniqKey="Rico Villademoros F">F Rico-Villademoros</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Montgomery, Sa" uniqKey="Montgomery S">SA Montgomery</name></author><author><name sortKey="Baldwin, Ds" uniqKey="Baldwin D">DS Baldwin</name></author><author><name sortKey="Riley, A" uniqKey="Riley A">A Riley</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ozbek, E" uniqKey="Ozbek E">E Ozbek</name></author><author><name sortKey="Tasci, Al" uniqKey="Tasci A">AL Tasci</name></author><author><name sortKey="Tugcu, V" uniqKey="Tugcu V">V Tugcu</name></author><author><name sortKey="Ilbey, Yo" uniqKey="Ilbey Y">YO Ilbey</name></author><author><name sortKey="Simsek, A" uniqKey="Simsek A">A Simsek</name></author><author><name sortKey="Ozcan, L" uniqKey="Ozcan L">L Ozcan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Perlis, Rh" uniqKey="Perlis R">RH Perlis</name></author><author><name sortKey="Laje, G" uniqKey="Laje G">G Laje</name></author><author><name sortKey="Smoller, Jw" uniqKey="Smoller J">JW Smoller</name></author><author><name sortKey="Fava, M" uniqKey="Fava M">M Fava</name></author><author><name sortKey="Rush, Aj" uniqKey="Rush A">AJ Rush</name></author><author><name sortKey="Mcmahon, Fj" uniqKey="Mcmahon F">FJ McMahon</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Phanjoo, At" uniqKey="Phanjoo A">AT Phanjoo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rosen, Rc" uniqKey="Rosen R">RC Rosen</name></author><author><name sortKey="Lane, Rm" uniqKey="Lane R">RM Lane</name></author><author><name sortKey="Menza, M" uniqKey="Menza M">M Menza</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rothschild, Aj" uniqKey="Rothschild A">AJ Rothschild</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Safarinejad, Mr" uniqKey="Safarinejad M">MR Safarinejad</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Safarinejad, Mr" uniqKey="Safarinejad M">MR Safarinejad</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Safarinejad, Mr" uniqKey="Safarinejad M">MR Safarinejad</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Schosser, A" uniqKey="Schosser A">A Schosser</name></author><author><name sortKey="Kasper, S" uniqKey="Kasper S">S Kasper</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Schweitzer, I" uniqKey="Schweitzer I">I Schweitzer</name></author><author><name sortKey="Maguire, K" uniqKey="Maguire K">K Maguire</name></author><author><name sortKey="Ng, C" uniqKey="Ng C">C Ng</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Segraves, Rt" uniqKey="Segraves R">RT Segraves</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Segraves, Rt" uniqKey="Segraves R">RT Segraves</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Serretti, A" uniqKey="Serretti A">A Serretti</name></author><author><name sortKey="Chiesa, A" uniqKey="Chiesa A">A Chiesa</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Serretti, A" uniqKey="Serretti A">A Serretti</name></author><author><name sortKey="Kato, M" uniqKey="Kato M">M Kato</name></author><author><name sortKey="De Ronchi, D" uniqKey="De Ronchi D">D De Ronchi</name></author><author><name sortKey="Kinoshita, T" uniqKey="Kinoshita T">T Kinoshita</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Smith, Sm" uniqKey="Smith S">SM Smith</name></author><author><name sortKey="O Keane, V" uniqKey="O Keane V">V O'Keane</name></author><author><name sortKey="Murray, R" uniqKey="Murray R">R Murray</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Stahl, Sm" uniqKey="Stahl S">SM Stahl</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Uher, R" uniqKey="Uher R">R Uher</name></author><author><name sortKey="Farmer, A" uniqKey="Farmer A">A Farmer</name></author><author><name sortKey="Maier, W" uniqKey="Maier W">W Maier</name></author><author><name sortKey="Rietschel, M" uniqKey="Rietschel M">M Rietschel</name></author><author><name sortKey="Hauser, J" uniqKey="Hauser J">J Hauser</name></author><author><name sortKey="Marusic, A" uniqKey="Marusic A">A Marusic</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Uher, R" uniqKey="Uher R">R Uher</name></author><author><name sortKey="Farmer, A" uniqKey="Farmer A">A Farmer</name></author><author><name sortKey="Henigsberg, N" uniqKey="Henigsberg N">N Henigsberg</name></author><author><name sortKey="Rietschel, M" uniqKey="Rietschel M">M Rietschel</name></author><author><name sortKey="Mors, O" uniqKey="Mors O">O Mors</name></author><author><name sortKey="Maier, W" uniqKey="Maier W">W Maier</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Uher, R" uniqKey="Uher R">R Uher</name></author><author><name sortKey="Huezo Diaz, P" uniqKey="Huezo Diaz P">P Huezo-Diaz</name></author><author><name sortKey="Perroud, N" uniqKey="Perroud N">N Perroud</name></author><author><name sortKey="Smith, R" uniqKey="Smith R">R Smith</name></author><author><name sortKey="Rietschel, M" uniqKey="Rietschel M">M Rietschel</name></author><author><name sortKey="Mors, O" uniqKey="Mors O">O Mors</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Uher, R" uniqKey="Uher R">R Uher</name></author><author><name sortKey="Maier, W" uniqKey="Maier W">W Maier</name></author><author><name sortKey="Hauser, J" uniqKey="Hauser J">J Hauser</name></author><author><name sortKey="Marusic, A" uniqKey="Marusic A">A Marusic</name></author><author><name sortKey="Schmael, C" uniqKey="Schmael C">C Schmael</name></author><author><name sortKey="Mors, O" uniqKey="Mors O">O Mors</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Uher, R" uniqKey="Uher R">R Uher</name></author><author><name sortKey="Perroud, N" uniqKey="Perroud N">N Perroud</name></author><author><name sortKey="Ng, My" uniqKey="Ng M">MY Ng</name></author><author><name sortKey="Hauser, J" uniqKey="Hauser J">J Hauser</name></author><author><name sortKey="Henigsberg, N" uniqKey="Henigsberg N">N Henigsberg</name></author><author><name sortKey="Maier, W" uniqKey="Maier W">W Maier</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Werneke, U" uniqKey="Werneke U">U Werneke</name></author><author><name sortKey="Northey, S" uniqKey="Northey S">S Northey</name></author><author><name sortKey="Bhugra, D" uniqKey="Bhugra D">D Bhugra</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Williams, V" uniqKey="Williams V">V Williams</name></author><author><name sortKey="Edin, H" uniqKey="Edin H">H Edin</name></author><author><name sortKey="Hogue, S" uniqKey="Hogue S">S Hogue</name></author><author><name sortKey="Fehnel, S" uniqKey="Fehnel S">S Fehnel</name></author><author><name sortKey="Baldwin, D" uniqKey="Baldwin D">D Baldwin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zisook, S" uniqKey="Zisook S">S Zisook</name></author><author><name sortKey="Rush, Aj" uniqKey="Rush A">AJ Rush</name></author><author><name sortKey="Haight, Br" uniqKey="Haight B">BR Haight</name></author><author><name sortKey="Clines, Dc" uniqKey="Clines D">DC Clines</name></author><author><name sortKey="Rockett, Cb" uniqKey="Rockett C">CB Rockett</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Allemagne</li><li>Belgique</li><li>Croatie</li><li>Danemark</li><li>Italie</li><li>Pologne</li><li>Royaume-Uni</li><li>Slovénie</li></country><region><li>Bade-Wurtemberg</li><li>District de Karlsruhe</li><li>Rhénanie-Palatinat</li></region><settlement><li>Mannheim</li><li>Trèves (Allemagne)</li></settlement><orgName><li>Université de Trèves</li></orgName></list><tree><country name="Allemagne"><region name="Bade-Wurtemberg"><name sortKey="Strohmaier, Jana" sort="Strohmaier, Jana" uniqKey="Strohmaier J" first="Jana" last="Strohmaier">Jana Strohmaier</name></region><name sortKey="Rietschel, Marcella" sort="Rietschel, Marcella" uniqKey="Rietschel M" first="Marcella" last="Rietschel">Marcella Rietschel</name><name sortKey="Schm L, Christine" sort="Schm L, Christine" uniqKey="Schm L C" first="Christine" last="Schm L">Christine Schm L</name><name sortKey="Streit, Fabian" sort="Streit, Fabian" uniqKey="Streit F" first="Fabian" last="Streit">Fabian Streit</name><name sortKey="Streit, Fabian" sort="Streit, Fabian" uniqKey="Streit F" first="Fabian" last="Streit">Fabian Streit</name><name sortKey="Wust, Stefan" sort="Wust, Stefan" uniqKey="Wust S" first="Stefan" last="Wüst">Stefan Wüst</name><name sortKey="Zobel, Astrid" sort="Zobel, Astrid" uniqKey="Zobel A" first="Astrid" last="Zobel">Astrid Zobel</name></country><country name="Royaume-Uni"><noRegion><name sortKey="Uher, Rudolf" sort="Uher, Rudolf" uniqKey="Uher R" first="Rudolf" last="Uher">Rudolf Uher</name></noRegion><name sortKey="Aitchison, Katherine J" sort="Aitchison, Katherine J" uniqKey="Aitchison K" first="Katherine J" last="Aitchison">Katherine J. Aitchison</name><name sortKey="Aitchison, Katherine J" sort="Aitchison, Katherine J" uniqKey="Aitchison K" first="Katherine J" last="Aitchison">Katherine J. Aitchison</name><name sortKey="Farmer, Anne" sort="Farmer, Anne" uniqKey="Farmer A" first="Anne" last="Farmer">Anne Farmer</name><name sortKey="Mcguffin, Peter" sort="Mcguffin, Peter" uniqKey="Mcguffin P" first="Peter" last="Mcguffin">Peter Mcguffin</name></country><country name="Croatie"><noRegion><name sortKey="Henigsberg, Neven" sort="Henigsberg, Neven" uniqKey="Henigsberg N" first="Neven" last="Henigsberg">Neven Henigsberg</name></noRegion></country><country name="Danemark"><noRegion><name sortKey="Mors, Ole" sort="Mors, Ole" uniqKey="Mors O" first="Ole" last="Mors">Ole Mors</name></noRegion></country><country name="Pologne"><noRegion><name sortKey="Hauser, Joanna" sort="Hauser, Joanna" uniqKey="Hauser J" first="Joanna" last="Hauser">Joanna Hauser</name></noRegion></country><country name="Belgique"><noRegion><name sortKey="Souery, Daniel" sort="Souery, Daniel" uniqKey="Souery D" first="Daniel" last="Souery">Daniel Souery</name></noRegion></country><country name="Slovénie"><noRegion><name sortKey="Dernovsek, Mojca Z" sort="Dernovsek, Mojca Z" uniqKey="Dernovsek M" first="Mojca Z" last="Dernovsek">Mojca Z. Dernovsek</name></noRegion><name sortKey="Kozel, Dejan" sort="Kozel, Dejan" uniqKey="Kozel D" first="Dejan" last="Kozel">Dejan Kozel</name></country><country name="Italie"><noRegion><name sortKey="Placentino, Anna" sort="Placentino, Anna" uniqKey="Placentino A" first="Anna" last="Placentino">Anna Placentino</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Rhénanie/explor/UnivTrevesV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000897 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000897 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Rhénanie
|area= UnivTrevesV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= PMC:3279131
|texte= Sexual dysfunction during treatment with serotonergic and noradrenergic antidepressants: Clinical description and the role of the 5-HTTLPR
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:21388237" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a UnivTrevesV1
| This area was generated with Dilib version V0.6.31. |  |